| ORIGINAL ARTICLE |
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| Year : 2020 | Volume
: 1
| Issue : 1 | Page : 20-24 |
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Computerized tomographic brain findings in HIV/AIDS patients on highly active antiretroviral therapy treatment presenting with central nervous system manifestations in Gombe, North-East, Nigeria
Philip Oluleke Ibinaiye1, Sefiya Adebanke Olarinoye-Akorede1, Suleiman T Sa'ad2, Nasiru M Tahir2, Sahkir Muhammad Balogun3, Aminu U Usman2, Abubakar Ali-Gombe4, Sani Garko2, Dahiru M Yunsa2, Timothy Y Umoru2, Bello O Usman5, Umar Abdulaziz4
1 Department of Radiology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
2 Department of Radiology, Federal Teaching Hospital, Gombe, Nigeria
3 Epidemiology and Strategic Information, Center for Disease Control, Abuja, Nigeria
4 Department of Medicine, Federal Teaching Hospital, Gombe, Nigeria
5 Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
Correspondence Address:
Dr. Sefiya Adebanke Olarinoye-Akorede
Department of Radiology, Ahmadu Bello University and Teaching Hospital Shika, Zaria
Nigeria
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/JRMT.JRMT_3_20
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Background: Despite the current availability of highly active antiretroviral therapy (HAART) in our hospital, neurologic complications of HIV still occur. Aim: The aim of this study was to document brain computed tomography (CT) findings in HIV patients receiving HAART who developed neurological complications and to examine the relationship of these findings with CD4 cell counts. Materials and Methods: Twenty patients with central nervous system symptoms out of 200 HIV/AIDS patients receiving HAART at the HIV Clinic of Federal Teaching Hospital, Gombe, were retrospectively studied. The findings were reviewed alongside their clinical features, CD4+ count, and HAART history. Results: CT findings were positive in 12 (60%) of the patients, while no abnormality was seen in 8 (40%) of the patients. The most common brain abnormality was atrophy (35%). Two out of 5 patients (40%) with CD4 counts >200 had abnormal CT findings compared with 9 out of 14 patients (64%) with CD4 counts <200 cells who had CT abnormalities. This finding was statistically significant (R = 0.864, P = 0.00). Conclusion: There is a high incidence of neurological complications and positive brain CT scans among the patients who defaulted from HAART treatment and with CD4 cell counts of <200 cells/μL.
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